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Neuroblastoma
  • Language: en
  • Pages: 262

Neuroblastoma

Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.

Approximation Algorithms
  • Language: en
  • Pages: 380

Approximation Algorithms

Covering the basic techniques used in the latest research work, the author consolidates progress made so far, including some very recent and promising results, and conveys the beauty and excitement of work in the field. He gives clear, lucid explanations of key results and ideas, with intuitive proofs, and provides critical examples and numerous illustrations to help elucidate the algorithms. Many of the results presented have been simplified and new insights provided. Of interest to theoretical computer scientists, operations researchers, and discrete mathematicians.

Ice Cream
  • Language: en
  • Pages: 483

Ice Cream

This edition of "Ice Cream" is a full revision of previous editions and includes an updating of the areas that have been affected by changes and new technolo gy. The ice cream industry has developed on the basis of an abundant economical supply of ingredients and is a high-volume, highly automated, modern, progressive, very competitive industry composed of large and small businesses manufacturing ice cream and related products. The industry un derwent a difficult period of adjusting to economic changes and to the es tablishment of product specifications and composition regulations. The latter area has now become more stabilized and the Frozen Desserts Definitions and Standards of Identity ar...

Handbook on Knowledge Management 2
  • Language: en
  • Pages: 738

Handbook on Knowledge Management 2

This second volume consists of the sections: technologies for knowledge management, outcomes of KM, knowledge management in action, and the KM horizon.

3D Image Processing
  • Language: en
  • Pages: 335

3D Image Processing

Few fields have witnessed such impressive advances as the application of computer technology to radiology. The progress achieved has revolutionized diagnosis and greatly facilitated treatment selection and accurate planning of procedures. This book, written by leading experts from many different countries, provides a comprehensive and up-to-date overview of the role of 3D image processing. The first section covers a wide range of technical aspects in an informative way. This is followed by the main section, in which the principal clinical applications are described and discussed in depth. To complete the picture, the final section focuses on recent developments in functional imaging and computer-aided surgery. This book will prove invaluable to all who have an interest in this complex but vitally important field.

Hormones
  • Language: en
  • Pages: 697

Hormones

Endocrinology is a field in which enormous advances have been made in the last decade; the rate of discovery of new hormones, hormone-like molecules, receptors, and mechanisms of action is continually advancing. The development of techniques in immunology and molecular biology has led to the possibility of describing in detail the gene structure of many of the compounds involved in hormonal systems. Remarkable homology has been shown between oncogene products and various components of the endocrine network, leading to the asser tion that deregulation of hormonal function is involved in the generation and/or development of cancer. We now know that the central nervous system is both a target a...

Early Warning Systems for Natural Disaster Reduction
  • Language: en
  • Pages: 834

Early Warning Systems for Natural Disaster Reduction

Written for a broad audience this book offers a comprehensive account of early warning systems for hydro meteorological disasters such as floods and storms, and for geological disasters such as earthquakes. One major theme is the increasingly important role in early warning systems played by the rapidly evolving fields of space and information technology. The authors, all experts in their respective fields, offer a comprehensive and in-depth insight into the current and future perspectives for early warning systems. The text is aimed at decision-makers in the political arena, scientists, engineers and those responsible for public communication and dissemination of warnings.

The Science and Business of Drug Discovery
  • Language: en
  • Pages: 397

The Science and Business of Drug Discovery

The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the nineteen chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has ...

Building Total Quality
  • Language: en
  • Pages: 303

Building Total Quality

Building Total Quality is an essential reference to all those involved in the construction of a total quality organisation

History of Science, History of Text
  • Language: en
  • Pages: 266

History of Science, History of Text

two main (interacting) ways. They constitute that with which exploration into problems or questions is carried out. But they also constitute that which is exchanged between scholars or, in other terms, that which is shaped by one (or by some) for use by others. In these various dimensions, texts obviously depend on the means and technologies available for producing, reproducing, using and organizing writings. In this regard, the contribution of a history of text is essential in helping us approach the various historical contexts from which our sources originate. However, there is more to it. While shaping texts as texts, the practitioners of the sciences may create new textual resources that...