Epileptology changes. The syndromic approach is completed by an etiological approach, based on the major advances in genetics and functional genetics. New entities have found their place, and a purely descriptive, “electroclinical” approach is no longer adapted in many circumstances. The 5th edition of the Blue Guide includes the most recent advances. It was necessary to justify the physiological, epidemiologic, genetic and therapeutic approaches and to consider them in the light of the new classification efforts, which are still in the making. Nevertheless, the description of epileptic syndromes, both classical and recent, remains at the core of this book.
The aim of this extensively illustrated work is to better the knowledge of visual analysis of EEGs for neurologists and other specialists who use electroencephalography as well as EEG technologists. This first volume covers the scope of the main features of physiological EEG wake and sleep activities in children and adults, activation procedures and the most commonly found artefacts. Indeed, a more thorough knowledge of these elements is necessary so as not to misinterpret them as pathological traits.
The need for neuropathology reviews in epilepsy surgery tissues steadily increases. However, textbooks and case presentations highlighting and focusing on this specific topic are rare. The authors of this book reviewed their professional experience in surgical and post-mortem neuropathology studies to compile a coherent summary of: clinico-pathological findings, current classification schemes, useful protocols research data for major histopathological entities of brain lesions encountered in modern epilepsy surgery programs, which is hippocampal sclerosis, brain tumours associated with early epilepsy onset, malformations of cortical development, brain inflammation and malformative vascular lesions. They did not intend to be exhaustive but rather representative of the main lesions and pathologies encountered. Thirty-two illustrated cases constitute the core of this book and will be very helpful in current practice.
Since its first description (1841) the identity of West syndrome was deeply investigated and is now recognized as an epileptic syndrome in infancy (ILAE Task Force, 1989). West syndrome has become a paradigmatic model of an epileptic syndrome causing neurological deterioration (epileptic encephalopathy) and the object of a number of studies aimed at understanding the complex relationships between an epileptic disorder and neurodevelopment. Although the symptomatic triad (peculiar electrographic findings named hypsarrhythmia, brief tonic spasms, and arrest of psychomotor development) that characterizes the syndrome suggests a unique pathogenetic mechanism, causal heterogeneity heavily influen...
Reflex epilepsies can provide a qualitative and quantitative viewpoint of the complexities of ictogenesis. The various chapters in this book examine the factors that can trigger a seizure, such as hot water, food, contact and movement, music and emotions. The relationship between several reflex epilepsy mechanisms and juvenile myoclonic epilepsy is discussed along with the significance of their occurrence in syndromes, enhancing our understanding of current epilepsy nosology. The conventional dichotomy appears outdated, while functional studies of trigger mechanisms are moving more towards central nervous system subsets acting as pathological networks that produce seizures in generalized and focal epilepsies.